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HomeProduct name listAld-PEG3-Azide

Ald-PEG3-Azide

Ald-PEG3-Azide Structural

What is Ald-PEG3-Azide?

Description

Ald-CH2-PEG3-azide is a click chemistry PEG linker. Aldehyde groups are likely to undergo nucleophile substitution, reduction and oxidation reactions. The azideN3 enable Click Chemistry reactions with alkynes, DBCO and BCN to form triazole groups. PEG3 spacer increases the water solubility of the compound.

Biological Activity

Ald-CH2-PEG3-azide is a cleavable 3-unit PEG-containing ADC linker that can be used to synthesize antibody drug conjugates (ADCs),it is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Properties of Ald-PEG3-Azide

solubility  Soluble in Water, DMSO, DMF, DCM

Safety information for Ald-PEG3-Azide

Computed Descriptors for Ald-PEG3-Azide

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