Azeliragon

CAS NO.：603148-36-3
Empirical Formula: C32H38ClN3O2
Molecular Weight: 532.12
MDL number: MFCD11977600
EINECS: 814-441-9
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-22 18:57:36

What is Azeliragon?

Biological Activity

Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule inhibitor that inhibits the receptor for advanced glycation end products (RAGE). RAGE is an immunoglobulin-like cell surface receptor that is overexpressed in the brains of Alzheimer's patients.

Properties of Azeliragon

Boiling point:	667.7±65.0 °C(Predicted)
Density	1.11±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO:50.33(Max Conc. mg/mL);94.58(Max Conc. mM) DMF:5.0(Max Conc. mg/mL);9.4(Max Conc. mM) DMF:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.62(Max Conc. mM) Ethanol:50.5(Max Conc. mg/mL);94.9(Max Conc. mM)
form	A crystalline solid
pka	10.16±0.25(Predicted)
color	White to light yellow

Safety information for Azeliragon

Computed Descriptors for Azeliragon

New Products

Hendecanoic acid 2-Amino-5-cyanopyridine 2-Bromo-5-cyanopyridine DL-3-Amino-3-(2-methoxyphenyl)propionic acid 3-Hydroxypropionitrile 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4,4-Diethoxybutanenitrile 5-Bromo-4-chloro-3-indolyl-β-D-galactopyranoside 6-(4-Amino-2,6-dichlorophenoxy)-4-isopropylpyridazin-3(2H)-one Tetracaine Hydrochloride Ep Grade 2,2,2-Trichloroethyl chloroformate 2-Bromo-6-fluoroaniline 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole 2-Aminobenzo[d]thiazol-4-ol Methyl 2-aminobutanoate hydrochloride 3-Fluoro-6-methylpicolinonitrile 1-(4-Aminopiperidin-1-yl)-3,3,3-trifluoropropan-1-one 5-chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one 3-cyanocyclohexane-1-carboxylic acid