ASIALOGANGLIOSIDE-GM2
Synonym(s):GA2 Ganglioside;Gangliotriosyl ceramide
- CAS NO.：35960-33-9
- Empirical Formula: C56H104N2O18
- Molecular Weight: 1093.42756
- MDL number: MFCD00131129
- Update Date: 2026-01-13 11:26:13
What is ASIALOGANGLIOSIDE-GM2?
Description
Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively. It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients. Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable lengths. [Matreya, LLC. Catalog No. 1512]
The Uses of ASIALOGANGLIOSIDE-GM2
Ganglioside GM2, Asialo is a semisynthetic ganglioside.
What are the applications of Application
Ganglioside GM2, Asialo is a semisynthetic ganglioside
General Description
Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.
Biochem/physiol Actions
Degraded form of Asialoganglioside-GM1 ganglioside.
Properties of ASIALOGANGLIOSIDE-GM2
| storage temp. | −20°C |
| solubility | Chloroform:Methanol:Water (2:1:0.1): Soluble |
| form | lyophilized powder |
Safety information for ASIALOGANGLIOSIDE-GM2
Computed Descriptors for ASIALOGANGLIOSIDE-GM2
New Products
2-(2-aminoethyl) benzenesulfonamide Gemcitabine 3-benzoate impurity Dihydroxyphenylacetone Ornidazole EP impurity D Acetyl amino diol impurity Valsartan Benzyl Ester Impurity B N,N'-Dicyclohexylcarbodiimide 3-Bromo-2-Methyl-5-Nitropyridine 5-Bromo-3-Methyl-2-Pyridinecarboxylic acid 2-Amino-4-Methylpyridine 4-Aminopyridine 4-dimethylaminopyridineRelated products of tetrahydrofuran
You may like
-
4-(Methylnitrosoamino)-butanal NLT 95%View Details
339362-86-6 -
848696-99-1 NLT 95%View Details
848696-99-1 -
Ornidazole EP impurity A 1384752-15-1 NLT 95%View Details
1384752-15-1 -
615-81-6 Diisopropyl oxalate NLT 95%View Details
615-81-6 -
175481-38-6 Lacosamide EP Impurity F NLT 95%View Details
175481-38-6 -
S-Clopidogrel N-Methyl Impurity 1346605-15-9 NLT 95%View Details
1346605-15-9 -
Valsartan Related Compound A NLT 95%View Details
137862-87-4 -
Losartan Propyl BCFI 124750-49-8 NLT 95%View Details
124750-49-8