Artemisinin-d3
- CAS NO.：176652-07-6
- Empirical Formula: C15H22O5
- Molecular Weight: 282.33218
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-20 16:56:08
What is Artemisinin-d3?
Description
Artemisinin-d3 is intended for use as an internal standard for the quantification of artemisinin . Artemisinin is an endoperoxide antimalarial agent with anticancer activity. It reduces the growth of various P. falciparum strains in vitro (IC50s = 3.98-20.36 nM) and reduces parasitemia in mice infected with P. falciparum with a curative dose (CD50) value of 140 mg/kg. It also reduces P. berghei infection in mice (ED50 = 5.6 mg/kg per day). Artemisinin (100-400 μM) induces cell cycle arrest in the G0/G1 phase and apoptosis and inhibits growth of SK-N-AS, BE(2)-C, SK-N-DZ, and SHEP1 neuroblastoma cells in a time- and concentration-dependent manner. It also suppresses BE(2)-C cell colony formation in a soft agar assay and reduces tumor growth in a BE(2)-C mouse xenograft model. Formulations containing artemisinin have been used in combination therapies for the treatment of malaria.
Chemical properties
Crystalline Solid
The Uses of Artemisinin-d3
Active antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial
Properties of Artemisinin-d3
| Melting point: | 156-157°C |
| storage temp. | -20°C Freezer |
| solubility | DMSO: Slightly soluble,Methanol: Slightly soluble |
| form | A solid |
| CAS DataBase Reference | 176652-07-6 |
Safety information for Artemisinin-d3
Computed Descriptors for Artemisinin-d3
New Products
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