ARP100
Synonym(s):(2-((Isopropoxy)-(1,1ʹ-biphenyl-4-ylsulfonyl)-amino))-N-hydroxyacetamide;MMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem
- CAS NO.：704888-90-4
- Empirical Formula: C17H20N2O5S
- Molecular Weight: 364.42
- MDL number: MFCD09971105
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is ARP100?
The Uses of ARP100
A selective inhibitor of MMP-2
What are the applications of Application
ARP 100 is a biphenylsulfonamide and selective inhibitor of MMP-2, also capable of suppressing the invasive behavior of HT1080 tumor cells.
Biological Activity
Selective inhibitor of MMP-2 (IC 50 = 12 nM); displays selectivity over MMP-9, MMP-3, MMP-1 and MMP-7 (IC 50 values are 200, 4500, > 50000 and > 50000 nM respectively). Exhibits anti-invasive properties in HT1080 fibrosarcoma cells.
Properties of ARP100
| storage temp. | Desiccate at +4°C |
| solubility | Soluble at 100mM in DMSO |
| form | Solid |
| color | Off-white to light yellow |
Safety information for ARP100
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for ARP100
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