Apatinib-d8 Hydrochloride
- CAS NO.：2468771-44-8
- Empirical Formula: C24H24ClN5O
- Molecular Weight: 433.93326
- MDL number: MFCD28138192
- Update Date: 2023-04-23 13:52:06
What is Apatinib-d8 Hydrochloride?
The Uses of Apatinib-d8 Hydrochloride
Labelled Apatinib (A726150). Apatinib is an orally available, small molecule multitargeted tyrosine kinase inhibitor. Apatinib selectively inhibits the vascular endothelial growth factor receptor-2 (V EGFR2). Apatinib functions by inhibiting VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Recent studies have shown that Apatinib e nhances the efficacy of conventional chemotherapeutical drugs in side population (SP) cells and ABCB1-overexpressing leukemia cells.
Properties of Apatinib-d8 Hydrochloride
| Melting point: | >192°C (dec.) |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Off-White to Pale Yellow |
Safety information for Apatinib-d8 Hydrochloride
Computed Descriptors for Apatinib-d8 Hydrochloride
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