AP1189 acetate
- CAS NO.：959850-74-9
- Empirical Formula: C14H14N6O2.C2H4O2
- Molecular Weight: 358.35
- Update Date: 2026-07-16 07:06:08
What is AP1189 acetate?
Description
AP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages. No melanogenesis was induced by AP1189 in B16-F10 melanocytes. In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ～3-fold.
Safety information for AP1189 acetate
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