Anti-RNF188

Synonym(s):Anti-Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1;Anti-HAKAI;

Molecular Weight: 0
Update Date: 2026-01-13 11:16:03

What is Anti-RNF188?

The Uses of Anti-RNF188

Anti-CBLL1, (N-terminal) antibody produced in rabbit is suitable for western blot analysis.

General Description

Epithelial cell cadherin (CDH1; MIM 192090) is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. HAKAI is an E3 ubiquitin ligase (see UBE3A; MIM 601623) that mediates ubiquitination of the CDH1 complex.[supplied by OMIM

Biochem/physiol Actions

CBLL1 (Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase) is an E-cadherin binding protein involved in the ubiquitination of E-cadherin and regulation of E-cadherin complex endocytosis. During ubiquitination, it directly binds to the cytoplasmic domain of E-cadherin. It has been reported in a study that CBLL1 may play a role in neuronal apoptosis and in LPS (Lipopolysaccharide) administration. CBLL1 have also been predicted as a regulator of cell proliferation.

Properties of Anti-RNF188

storage temp.	-20°C
form	buffered aqueous solution

Safety information for Anti-RNF188

Computed Descriptors for Anti-RNF188

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