Anti-PRKC, apoptosis, WT1, Regulator

The Uses of Anti-PRKC, apoptosis, WT1, Regulator

Rabbit Anti-PAWR (AB1) antibody can be used for western blot applications at a concentration of 1μg/ml.

General Description

PAWR is a transcriptional repressor that has a leucine zipper domain. Genetic variations in PAWR have been linked to major depressive disorder (MDD) and schizophrenia.
Rabbit Anti-PAWR (AB2) antibody recognizes human, mouse, and rat PAWR.

Biochem/physiol Actions

The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.