Anti-NET62

The Uses of Anti-NET62

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

General Description

The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

Biochem/physiol Actions

Malonyl-CoA-acyl carrier protein transacylase (MCAT) is an important enzyme involved in the fatty-acid biosynthesis pathway of bacteria. This enzyme catalyzes the transfer of a malonyl group from malonyl–CoA to the free thiol group of the phosphopantetheine arm of acyl carrier protein. In addition, it is also implicated in polyketide biosynthesis, producing one of the largest classes of secondary metabolites, such as the tetracyclines and erythromycins. Hence, MCAT is considered as a key enzyme in bacterial metabolic activity. This enzyme also serves as a potential drug target in the discovery of antibacterial agents.