Amcinafide
- CAS NO.：7332-27-6
- Empirical Formula: C29H33FO6
- Molecular Weight: 496.57
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-12-21 16:56:50
What is Amcinafide?
Originator
Amcinafide,Onbio Inc.
The Uses of Amcinafide
Anti-inflammatory.
Manufacturing Process
1 ml 72% perchloric acid was added to a suspension of 4 g triamcinolone in 100 ml of fresh distilled acetophenone and the mixture was stirred at a room temperature before all triamcinolone solved (for about 2 hours). The solution was neutralized with help of 8 ml of 1.1 N sodium hydroxide and sufficient quantity of sodium bicarbonate. Then chloroform and water were added. Organic layer was separated and concentrated in vacuum. The residue was recrystallized from acetone-hexane and thoroughly washed from acetophenone with hexane. Triamcinolone acetophenide (amicinafide) was prepared. It had MP: 281°-283°C (decomp.);αD 23 = +23°. (c = 0.98 in CHCl3).
Therapeutic Function
Antiinflammatory, Antiallergic
Safety information for Amcinafide
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