AM 5262
- CAS NO.:1222088-90-5
- Empirical Formula: C33H35FO4
- Molecular Weight: 514.63
- MDL number: MFCD28386343
- Update Date: 2026-04-24 14:58:13
What is AM 5262?
Description
AM-5262 is a Potent GPR40 Full Agonist with improved rat PK profile and general selectivity profile. AM-5262 enhanced glucose stimulated insulin secretion (mouse and human islets) and improved glucose homeostasis in vivo (OGTT in HF/STZ mice) when compared to AM-1638. GPR40 (FFAR1 or FFA1) is a target of high interest being pursued to treat type II diabetes due to its unique mechanism leading to little risk of hypoglycemia.
Properties of AM 5262
| Boiling point: | 657.7±55.0 °C(Predicted) |
| Density | 1.26±0.1 g/cm3(Predicted) |
| pka | 4.71±0.20(Predicted) |
Safety information for AM 5262
Computed Descriptors for AM 5262
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