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HomeProduct name listAM 5262

AM 5262

  • CAS NO.:1222088-90-5
  • Empirical Formula: C33H35FO4
  • Molecular Weight: 514.63
  • MDL number: MFCD28386343
  • Update Date: 2026-04-24 14:58:13
AM 5262 Structural

What is AM 5262?

Description

AM-5262 is a Potent GPR40 Full Agonist with improved rat PK profile and general selectivity profile. AM-5262 enhanced glucose stimulated insulin secretion (mouse and human islets) and improved glucose homeostasis in vivo (OGTT in HF/STZ mice) when compared to AM-1638. GPR40 (FFAR1 or FFA1) is a target of high interest being pursued to treat type II diabetes due to its unique mechanism leading to little risk of hypoglycemia.

Properties of AM 5262

Boiling point: 657.7±55.0 °C(Predicted)
Density  1.26±0.1 g/cm3(Predicted)
pka 4.71±0.20(Predicted)

Safety information for AM 5262

Computed Descriptors for AM 5262

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