ALPHA-BUNGAROTOXIN
Synonym(s):α-Bungarotoxin, Bungarus multicinctus - CAS 11032-79-4 - Calbiochem
- CAS NO.：11032-79-4
- Empirical Formula: C50H70O14
- Molecular Weight: 895.0824
- MDL number: MFCD01779815
- EINECS: 234-266-6
- Update Date: 2026-05-27 23:34:36
What is ALPHA-BUNGAROTOXIN?
Chemical properties
Single polypeptide weight; molecular weight of 8000.
What are the applications of Application
α-Bungarotoxin is an α-neurotoxin which competitively and irreversibly binds and blocks nAChR
Definition
A protein that binds specifically to acetylcholine receptors.
General Description
Blocks neuromuscular transmission by irreversible binding to motor end-plate acetylcholine receptor (Kd = 1 pM to 1 nM) but does not depress acetylcholine release from motor nerve endings. Blocks nicotine-induced increase of intracellular Ca2+ in PC12 cells (IC50 = 310 nM), and prevents opening of nicotinic receptor-associated ion channels. Reconstitution experiments in Xenopus oocytes have shown the effects of α-bungarotoxin on neuronal nAChR to be highly specific for the α7-subtype (IC50 = 1.6 nM), but not for the α3β4-subtype (IC50 >3 μM).
Hazard
Nuerotoxic.
Biochem/physiol Actions
Product does not compete with ATP.
Storage
-20°C (desiccate)
Properties of ALPHA-BUNGAROTOXIN
| storage temp. | −20°C |
| solubility | Soluble in sterile water |
| form | solid |
| color | white |
| Water Solubility | Soluble in water |
| CAS DataBase Reference | 11032-79-4 |
Safety information for ALPHA-BUNGAROTOXIN
Computed Descriptors for ALPHA-BUNGAROTOXIN
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 2,4-Dihydroxybenzaldehyde Dipropyl disulfide Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Obidoxime hydrochloride API 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
You may like
-
α-Bungarotoxin, Bungarus multicinctus CAS 11032-79-4View Details
11032-79-4 -
471-25-0 Propiolic Acid 98+View Details
471-25-0 -
84145-28-8 98+View Details
84145-28-8 -
trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 98+View Details
63909-29-5 -
2-(2-Chlorophenyl)glycine 88744-36-9 98+View Details
88744-36-9 -
40216-83-9 trans-4-Hydroxy-L-proline methyl ester hydrochloride 98+View Details
40216-83-9 -
629-76-5 98+View Details
629-76-5 -
1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene 98+View Details
39816-35-8