α-Apo-oxytetracycline

CAS NO.：18695-01-7
Empirical Formula: C22H22N2O8
Molecular Weight: 442.42
MDL number: MFCD29916779
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-24 14:58:57

What is α-Apo-oxytetracycline?

Chemical properties

khaki-coloured crystalline powder

The Uses of α-Apo-oxytetracycline

Oxytetracycline metabolite (absolute stereochemistry unknown)

The Uses of α-Apo-oxytetracycline

α-Apooxytetracycline is a degradation product of oxytetracycline, formed under acidic conditions. An initial dehydration to anhydrooxytetracycline then undergoes an internal cyclisation of the C5-OH to the C12 ketone. The resulting cleavage of the C12-C12a bond generates two isomers, α- and β-apooxytetracycline. α-apooxytetracycline is an important standard for monitoring oxytetracycline stability.

The Uses of α-Apo-oxytetracycline

α-Apooxytetracycline is a degradation product of oxytetracycline, formed under acidic conditions. After initial dehydration to anhydrooxytetracycline, it undergoes an internal cyclisation of the C5-OH to the C12 ketone. The resulting cleavage of the C12-C12a bond generates two isomers, α- and β-apooxytetracycline. α-Apooxytetracycline is an important standard for monitoring oxytetracycline stability.

What are the applications of Application

α-Apo-oxytetracycline is An metabolite Oxytetracycline

Properties of α-Apo-oxytetracycline

Melting point:	200°C
Boiling point:	742.4±60.0 °C(Predicted)
Density	1.62±0.1 g/cm3(Predicted)
storage temp.	Refrigerator, Under Inert Atmosphere
solubility	Aqueous Base (Slightly), Methanol (Slightly)
pka	1.62±0.58(Predicted)
form	Crystalline Powder
color	Khaki
Stability:	Hygroscopic, Unstable in basic solution
EPA Substance Registry System	1-Cyclohexene-1-carboxamide, 4-(1,3-dihydro-4,5-dihydroxy-9-methyl-3-oxonaphtho[2,3-c]furan-1-yl)-3-(dimethylamino)-2,5-dihydroxy-6-oxo-, stereoisomer (18695-01-7)