alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride

CAS NO.：326-43-2
Empirical Formula: C13H15ClN2O
Molecular Weight: 250.724
MDL number: MFCD00242757
EINECS: 2063083
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-27 23:49:48

What is alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride ?

Originator

Analexin, Mallinckrodt Inc., US ,1960

The Uses of alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride

Analgesic; relaxant (skeletal muscle).

Manufacturing Process

A mixture containing 188 g (0.20 mol) of 2-arninopyridine, 0.55 g of lithium amide and 75 cc of anhydrous toluene was refluxed for 1.5 hours. Styrene oxide (12.0 g = 0.10 mol) was then added to the reaction mixture with stirring over a period of ten minutes. The reaction mixture was stirred and refluxed for an additional 3.5 hours. A crystalline precipitate was formed during the reaction which was removed by filtration, MP 170°C to 171°C. 1.5 g. The filtrate was concentrated to dryness and a dark residue remained which was crystallized from anhydrous ether; yield 6.0 g. Upon recrystallization of the crude solid from 30 cc of isopropyl alcohol, 2.0 g of a light yellow solid was isolated; MP 170° to 171°C.

Therapeutic Function

Analgesic, Muscle relaxant

Properties of alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride

Melting point:

140-142°

Safety information for alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride

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