Alkyne NHS ester (hexynoic acid NHS ester)
- CAS NO.：906564-59-8
- Empirical Formula: C10H11NO4
- Molecular Weight: 209.2
- MDL number: MFCD28898858
- Update Date: 2025-08-05 17:23:08
What is Alkyne NHS ester (hexynoic acid NHS ester)?
Description
5-Hexynoic Acid-NHS Ester contains a propargyl group and an NHS ester group. This reagent is an amine reactive reagent for derivatizing peptides, antibodies, amine coated surfaces etc. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
The Uses of Alkyne NHS ester (hexynoic acid NHS ester)
5-Hexynoic NHS Ester is a nonclaevable linker for antibody-drug-conjugation. 5-Hexynoic NHS Ester is used in the preparation of biomimetic G-quartet compounds for detection, imaging and purification of G-quartet nucleic acids.
Properties of Alkyne NHS ester (hexynoic acid NHS ester)
| form | Liquid |
| color | Colorless to light yellow |
Safety information for Alkyne NHS ester (hexynoic acid NHS ester)
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Alkyne NHS ester (hexynoic acid NHS ester)
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