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AF12198

AF12198 Structural

What is AF12198?

The Uses of AF12198

AF 12198 is a peptide that selectively binds Interleukin-1 (IL-1) receptor and blocks in vivo responses to IL-1 (1). The interleukin-1 receptor can activate the innate immune response by binding to cytokines (2). Dysregulation of cytokine production can lead to aberrant immune cells activation that could result in auto-inflammatory disorders.

Storage

Store at -20°C

Properties of AF12198

Melting point: >179°C (dec.)
Density  1.353±0.06 g/cm3(Predicted)
storage temp.  −20°C
solubility  DMSO (Slightly), Methanol (Slightly), Water (Very Slightly)
form  solid
pka 4.44±0.10(Predicted)
color  White to Off-White

Safety information for AF12198

Computed Descriptors for AF12198

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