Abunidazole
- CAS NO.：91017-58-2
- Empirical Formula: C15H19N3O4
- Molecular Weight: 305.332
- MDL number: MFCD00868673
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 19:39:08
What is Abunidazole?
Originator
Abunidazole,ZYF Pharm Chemical
Manufacturing Process
150.0 g (1 mol) of p-tert-butylphenol are dissolved in 1200 ml of anhydrous
ethyl ether and the thus obtained solution is added to a 10% solution of
ethylmagnesium bromide in 1000 ml of anhydrous ether, at room
temperature, under stirring.
After having evaporated the ether, 1000 ml of anhydrous benzene are added and the mixture is distilled, at normal pressure, until its volume is about 2/3
of the original volume. After cooling at room temperature, 1 mol of 1-methyl-
5-nitroimidazolyl-2-carboxyaldehyde in 1000 ml of anhydrous benzene is
added.
The whole is boiled for 1 h, is cooled to about 10°C and is added with 8% HCl
to adjust the pH to 7. Benzene layer is dried and concentrated up to 2/3 of
the volume. The 2-(1-methyl-5-nitro)imidazolyl-1-(2-hydroxy-5-tertbutylphenylcarbinol
is allowed to crystallize, melting point 158°-160°C; yield
0-60%.
Therapeutic Function
Antiprotozoal
Properties of Abunidazole
| Boiling point: | 529.4±50.0 °C(Predicted) |
| Density | 1.30±0.1 g/cm3(Predicted) |
| pka | 9.57±0.48(Predicted) |
Safety information for Abunidazole
Computed Descriptors for Abunidazole
New Products
2-Bromo-4-hydroxypyridine 2-Benzyl-1,1,3,3-tetramethylisoindoline AMINO-O-TOLYL-ACETIC ACID AMINO(2-BROMOPHENYL)ACETIC ACID 6-BROMOTETRAZOLO[1,5-A]PYRIDINE 3-Oxocyclobutanecarboxylic acid 1,3-Diazaspiro[4.5]decane-2,4-dione, 8,8-difluoro- AMINO-(3-FLUORO-PHENYL)-ACETIC ACID Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Obidoxime hydrochloride API Piperazine, 1-(3-methoxyphenyl)-, hydrochloride (1:1) Decanoic acid, 2-[4-(phenylmethoxy)phenyl]ethyl ester 2,4-Dihydroxybenzaldehyde 3-Cyano-4-(2-methylpropoxy)benzenecarbothioamide 1-(2, 4-dichlorophenyl)-N-(2, 4-difluorophenyl)-N isopropyl-5-oxo-1H-1, 2, 4-trizole-4(5H)-carboxamide 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
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