ABD-F
Synonym(s):4-(Aminosulfonyl)-7-fluorobenzofurazane;7-Fluoro-2,1,3-benzoxadiazole-4-sulfonamide;7-Fluorobenzofurazan-4-sulfonamide;ABD-F
- CAS NO.：91366-65-3
- Empirical Formula: C6H4FN3O3S
- Molecular Weight: 217.18
- MDL number: MFCD00036687
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-29 15:43:00
What is ABD-F?
Chemical properties
Light Yellow Solid
The Uses of ABD-F
Highly reactive fluorogenic reagent for the labeling of thiols for HPLC. ABD-F is nonfluorescent until reacted with thiols and therefore can be used to quantitate thiols in solution, as well as thiols separated by HPLC or TLC.
The Uses of ABD-F
A water soluble pH dependent bifunctional fluorogenic reagent for the sensitive and specific detection of protein thiols. ABD-F is highly reactive and specific for protein thiols, and its selectivity is superior to that of other sulfhydryl-reactive fluorophores such as fluorescein maleimide, 5-iodoacetamidofluorescein, 5-I-AEDANS, dansylaziridine, and bimane. Fluorescence: max Abs. l = 385nm, max Em. l = 520nm; Molar Abs. > 4.5x103 (ca. 315nm)
The Uses of ABD-F
Reagent for fluorimetric assay of thiols.
What are the applications of Application
ABD-F is a vasorelaxant and fluorogenic reagent for selectively labelling protein cysteine residues inside thiol compounds.
General Description
4-Fluoro-7-sulfamoylbenzofurazan is a fluorescent reagent, which directly links to the sulfur atom of thiols without a flexible alkyl chain. It is used to detect low molecular thiols using high performance liquid chromatography.
Properties of ABD-F
| Melting point: | 143-145°C |
| Boiling point: | 408.8±55.0 °C(Predicted) |
| Density | 1.724±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: soluble |
| form | White to yellow crystalline powder. |
| pka | 9.08±0.30(Predicted) |
| color | Off-White to Pale Yellow |
| BRN | 5035147 |
| Stability: | Light Sensitive |
Safety information for ABD-F
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for ABD-F
| InChIKey | XROXHZMRDABMHS-UHFFFAOYSA-N |
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