Abacavir Triphosphate TEA Salt

Molecular Weight: 0
Update Date: 2023-04-23 13:52:06

What is Abacavir Triphosphate TEA Salt?

The Uses of Abacavir Triphosphate TEA Salt

Abacavir Triphosphate TEA Salt, is a metabolite of Abacavir. Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

What are the applications of Application

Abacavir Triphosphate TEA Salt is a nucleoside reverse transcriptase inhibitor (NRTI)

Properties of Abacavir Triphosphate TEA Salt

Melting point:	>104C (dec.)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	Methanol (Slightly), Water (Slightly)
form	Solid
color	Off-White to Pale Beige

Safety information for Abacavir Triphosphate TEA Salt

Computed Descriptors for Abacavir Triphosphate TEA Salt

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