A 39183A
- CAS NO.:79426-51-0
- Empirical Formula: C34H30O10
- Molecular Weight: 598.6
- MDL number: MFCD33021109
- Update Date: 2026-05-11 16:31:51
What is A 39183A?
Description
A-39183A is an active component of the A-39183 antibiotic complex produced by aerobic fermentation of Streptomyces NRRL 12049. It has activity against penicillin-resistant S. aureus 3055 and S. faecalis X66 (MICs = 32 and 32 μg/ml, respectively) and a variety of Gram-positive and Gram-negative anaerobic bacteria (MICs = 16-128 μg/ml) in an agar dilution assay.
The Uses of A 39183A
A 39183A is a rare 9,9’-bianthryl antibiotic related to setomimycin isolated from a strain of Streptomyces by researchers at Eli Lilly, USA, in 1981. A 39183A has broad spectrum antibiotic activity against both susceptible and resistant isolates including many anaerobic species. The patent reported that A 38183A acts as an ionophore, aiding the partitioning of Mg+ and Ca+ ions into organic solvents and transport of ferric ions into mitochondria.
Properties of A 39183A
| Boiling point: | 790.1±60.0 °C(Predicted) |
| Density | 1.509±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble |
| form | A solid |
| pka | 3.36±0.60(Predicted) |
Safety information for A 39183A
Computed Descriptors for A 39183A
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