(9S)-9-Amino-9-deoxoerythromycin

Chemical properties

(9S)-9-Amino-9-deoxoerythromycin is White Solid

The Uses of (9S)-9-Amino-9-deoxoerythromycin

(9S)-9-Amino-9-deoxoerythromycin is a metabolite of Dirithromycin; an antibiotic

The Uses of (9S)-9-Amino-9-deoxoerythromycin

(9S)-9-Amino-9-deoxoerythromycin is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. (9S)-9-Amino-9-deoxoerythromycin is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. This limitation was overcome by the synthesis of dirithromycin, a Schiff base pro-drug that dissociates in vivo to erythromycylamine.

The Uses of (9S)-9-Amino-9-deoxoerythromycin

Erythromycylamine is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. Erythromycylamine is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. This limitation was overcome by the synthesis of dirithromycin, a Schiff base pro-drug that dissociates in vivo to erythromycylamine.

What are the applications of Application

Erythromycylamine is a semi-synthetic analogue of erythromycin, a potent antibiotic

Definition

ChEBI: A macrolide antibiotic that is erythromycin A in which the ketone group has been converted to the corresponding imine and then reduced to give the corresponding amino compound (the 9S diastereoisomer).