9[3[(1methylethyl)amino]propyl]-fluorene-9-carboxamide

Absorption

Nearly complete following oral administration.

Toxicity

When given orally to either young adult rats or mice, the LD50 was 100 mg/kg. Symptoms of overdose include nausea and vomiting, convulsions, hypotension, bradycardia, syncope, extreme widening of the QRS complex, widening of the QT interval, widening of the PR interval, ventricular tachycardia, AV nodal block, asystole, bundle branch block, cardiac failure, and cardiac arrest.

The Uses of 9[3[(1methylethyl)amino]propyl]-fluorene-9-carboxamide

Cardiac depressant (anti-arrhythmic).

Background

Indecainide is a rarely used antidysrhythmic. Indecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.

Indications

For the treatment of life-threatening dysrhythmias and sustained ventricular tachycardia.

Definition

ChEBI: Indecainide is a member of fluorenes.

brand name

Decabid (Lilly).

Pharmacokinetics

Indecainide is a rarely used antidysrhythmic. Indecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.

Metabolism

Not Available