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HomeProduct name list10-Methoxycamptothecin

10-Methoxycamptothecin

10-Methoxycamptothecin Structural

What is 10-Methoxycamptothecin?

Description

A minor constituent of Mappia foetida Miers. The alkaloid yields pale yellow crystals when purified from CHC13-MeOH. It is laevorotatory with [α]24D - 77.5° (c 1.0, pyridine). The structure has been established by spectroscopic methods.

The Uses of 10-Methoxycamptothecin

9-Methoxycamptothecin is an alkaloid derivative of Camptothecin (C175150) derivative used in the treatment of cancers. Camptothecin is a potent anti-cancer agent.

The Uses of 10-Methoxycamptothecin

10-Methoxycamptothecin is a Camptothecin (C175150) derivative used in the treatment of cancers. Used in the treatment of hyperproliferative diseases.

References

Govindachari, Viswanathan., Phytochem., 11, 3529 (1972)
Govindachari, Viswanathan.,Ind. J. Chem., 10,453 (1972)

Properties of 10-Methoxycamptothecin

Melting point: 254-255℃
Boiling point: 773.1±60.0 °C(Predicted)
Density  1.50
storage temp.  4°C, protect from light
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form  Cryst.
pka 11.21±0.20(Predicted)
color  White to yellow

Safety information for 10-Methoxycamptothecin

Computed Descriptors for 10-Methoxycamptothecin

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