8-Cyclohexadecanone
- CAS NO.：3100-36-5
- Empirical Formula: C16H28O
- Molecular Weight: 236.39
- MDL number: MFCD00012389
- EINECS: 401-700-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:56:28
What is 8-Cyclohexadecanone?
Chemical properties
8-CYCLOHEXADECANONE is a viscous, clear, colorless to slightly yellow liquid with an
elegant, fine, erogenous musk odor with a unique, sweet, powdery nitro musk
undertone and balsamic, tobacco-like shades.
Due to its excellent stability and long-lasting properties, it is recommended for
nearly all perfumery applications, especially for fine fragrances, personal care, and
fabric care perfumes.
(E/Z)-8-Cyclohexadecenone is manufactured by monoepoxidation of
1,9-cyclohexadecadiene and subsequent rearrangement of the epoxide to the
ketone.The starting material, 1,9-cyclohexadecadiene, is obtained from
two molecules of cyclooctene by a metathesis reaction.
The Uses of 8-Cyclohexadecanone
Animusk is a fragrant macrocyclic ketone that have been shown to have antitumor and antiinvasive effects on human fibrosarcoma cell.
Synthesis Reference(s)
The Journal of Organic Chemistry, 33, p. 4541, 1968 DOI: 10.1021/jo01276a058
Flammability and Explosibility
Not classified
Trade name
Globanone® (Symrise)
Properties of 8-Cyclohexadecanone
| Melting point: | 22 °C |
| Boiling point: | 193 °C |
| Density | 0.863±0.06 g/cm3(Predicted) |
| vapor pressure | 0.029Pa at 25℃ |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Oil to Low-Melting Solid |
| color | Colourless to Off-White |
| Odor | at 10.00 % in dipropylene glycol. musk clean laundered cloth dry balsamic waxy animal floral tobacco |
| Water Solubility | 1.09mg/L at 20℃ |
| EPA Substance Registry System | 8-Cyclohexadecen-1-one (3100-36-5) |
Safety information for 8-Cyclohexadecanone
Computed Descriptors for 8-Cyclohexadecanone
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