8-CYCLOHEXADECANONE

Chemical properties

8-CYCLOHEXADECANONE is a viscous, clear, colorless to slightly yellow liquid with an elegant, fine, erogenous musk odor with a unique, sweet, powdery nitro musk undertone and balsamic, tobacco-like shades.
Due to its excellent stability and long-lasting properties, it is recommended for nearly all perfumery applications, especially for fine fragrances, personal care, and fabric care perfumes.
(E/Z)-8-Cyclohexadecenone is manufactured by monoepoxidation of 1,9-cyclohexadecadiene and subsequent rearrangement of the epoxide to the ketone.The starting material, 1,9-cyclohexadecadiene, is obtained from two molecules of cyclooctene by a metathesis reaction.

The Uses of 8-CYCLOHEXADECANONE

Animusk is a fragrant macrocyclic ketone that have been shown to have antitumor and antiinvasive effects on human fibrosarcoma cell.

Synthesis Reference(s)

The Journal of Organic Chemistry, 33, p. 4541, 1968 DOI: 10.1021/jo01276a058

Flammability and Explosibility

Not classified

Trade name

Globanone® (Symrise)