7,8-DIHYDROXY-6-METHOXYCOUMARIN
Synonym(s):7,8-Dihydroxy-6-methoxycoumarin;Fraxetin
- CAS NO.：574-84-5
- Empirical Formula: C10H8O5
- Molecular Weight: 208.17
- MDL number: MFCD00006873
- EINECS: 209-376-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-16 19:33:17
What is 7,8-DIHYDROXY-6-METHOXYCOUMARIN?
The Uses of 7,8-DIHYDROXY-6-METHOXYCOUMARIN
Fraxetin is a coumarin compound with anti-oxidant and anti-inflammatory activity. Also acts as a protective agent against hyperuricemia and renal dysfunction.
Definition
ChEBI: Fraxetin is a hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups. It has a role as an Arabidopsis thaliana metabolite, an antimicrobial agent, an apoptosis inhibitor, an apoptosis inducer, an antioxidant, an anti-inflammatory agent, a hepatoprotective agent, an antibacterial agent and a hypoglycemic agent. It is a hydroxycoumarin and an aromatic ether.
Properties of 7,8-DIHYDROXY-6-METHOXYCOUMARIN
| Melting point: | 230-231 °C (lit.) |
| Boiling point: | 307.35°C (rough estimate) |
| Density | 1.3844 (rough estimate) |
| refractive index | 1.4717 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO : 250 mg/mL (1200.94 mM; Need ultrasonic) |
| form | neat |
| pka | 7.22±0.20(Predicted) |
| form | Solid |
| color | White |
| Merck | 13,4288 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 574-84-5(CAS DataBase Reference) |
Safety information for 7,8-DIHYDROXY-6-METHOXYCOUMARIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for 7,8-DIHYDROXY-6-METHOXYCOUMARIN
| InChIKey | HAVWRBANWNTOJX-UHFFFAOYSA-N |
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