7-Nitroindole
Synonym(s):NSC 69874
- CAS NO.:6960-42-5
- Empirical Formula: C8H6N2O2
- Molecular Weight: 162.15
- MDL number: MFCD00005683
- EINECS: 677-504-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-29 08:43:58
What is 7-Nitroindole?
Chemical properties
yellow crystalline powder
The Uses of 7-Nitroindole
7-Nitroindole is a reagent used in chemical synthesis. It has been used in the synthesis of protein kinase and inosine monophosphate inhibitors, beta3 agonists and CCK-1 receptor modulators. 7-Nitroindole has also been used as a photochemical precursor of the 2'-deoxyribonolactone analog.
The Uses of 7-Nitroindole
7-Nitroindole is a useful reactant for the preparation of various compounds and inhibitors.
The Uses of 7-Nitroindole
Reactant for preparation of:
- Protein kinase inhibitors
- Potential fructose 1,6-bisphosphatase inhibitors
- Factor Xa inhibitors
- Antagonist of the mineralocorticoid receptor
- Antitumor sulfonamides
- Inosine monophosphate dehydrogenase (IMPDH) inhibitors
- Subtype-selective cyclooxygenase (COX) inhibitors
- Thrombin protease-activated receptor (PAR-1) ligands
What are the applications of Application
7-Nitroindole is 7-Nitroindole is a reactant for preparation of protein kinase inhibitors, Factor Xa inhibitors, subtype-selective cyclooxygenase (COX) inhibitors, and Thrombin protease-activated receptor (PAR-1) ligands.
What are the applications of Application
Reactant for preparation of:
Protein kinase inhibitors
Potential fructose 1,6-bisphosphatase inhibitors
Factor Xa inhibitors
Antagonist of the mineralocorticoid receptor
Antitumor sulfonamides
Inosine monophosphate dehydrogenase (IMPDH) inhibitors
Subtype-selective cyclooxygenase (COX) inhibitors
Thrombin protease-activated receptor (PAR-1) ligands
Synthesis Reference(s)
Canadian Journal of Chemistry, 42, p. 1235, 1964 DOI: 10.1139/v64-189
Properties of 7-Nitroindole
| Melting point: | 94-98 °C (lit.) |
| Boiling point: | 288.82°C (rough estimate) |
| Density | 1.3264 (rough estimate) |
| refractive index | 1.5770 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 13.96±0.30(Predicted) |
| form | powder to crystal |
| color | Light yellow to Yellow to Orange |
| Water Solubility | slightly soluble |
| BRN | 130874 |
| CAS DataBase Reference | 6960-42-5(CAS DataBase Reference) |
Safety information for 7-Nitroindole
| Signal word | Warning |
| Pictogram(s) |
![]() Health Hazard GHS08 |
| GHS Hazard Statements |
H341:Germ cell mutagenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. |
Computed Descriptors for 7-Nitroindole
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