7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
Synonym(s):1H-Pyrrole-2,5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)-;Anti-Carboxypeptidase M precursor antibody produced in rabbit;Carboxypeptidase M;CPM
- CAS NO.：76877-33-3
- Empirical Formula: C24H22N2O4
- Molecular Weight: 402.44
- MDL number: MFCD00077334
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 05:13:16
What is 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin?
Description
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe. It displays excitation/emission maxima of 387/468 nm, respectively, and fluorescence intensity increases when bound to cysteine residues.
The Uses of 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
(7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin)CPM is probably the most widely used blue fluorescent thiol-reactive dye. This maleimide derivative of coumarin is essentially nonfluorescent until it reacts with thiols, making it possible to quantify thiols without a separation step. CPM is a good energ
The Uses of 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe. 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (CPM) is a thiol-reactive fluorescent probe. CPM selectively forms Michael adducts in the presence of hyperreactive sulfhydryls. CPM has been used to monitor the release of thiols, quantitate thiol in microplate reactions, and to distinguish proliferating cancer cells by nucleolar protein staining. Dyes and metabolites.
What are the applications of Application
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe
Properties of 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
| Melting point: | 220-223°C |
| Boiling point: | 618.7±55.0 °C(Predicted) |
| Density | 1.302±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: soluble |
| pka | 3.28±0.20(Predicted) |
| form | solid |
| color | yellow |
Safety information for 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
Computed Descriptors for 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
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