7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
- CAS NO.：16600-22-9
- Empirical Formula: C12H10ClNO3
- Molecular Weight: 251.67
- MDL number: MFCD00438741
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-02 19:21:55
What is 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER?
Chemical properties
Crystalline compounds. Melting point 297 ℃.
The Uses of 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can be used as an intermediate of chloroquine.
Synthesis
Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can be obtained by heating and condensing m-chloroaniline and triethyl orthoformate, then condensing with diethyl malonate with the participation of boron trifluoride, and finally heating and cyclizing in paraffin oil.
Properties of 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
| Melting point: | 296-298℃ |
| Boiling point: | 366.8±37.0 °C(Predicted) |
| Density | 1.386 |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 2.18±0.50(Predicted) |
Safety information for 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
| Signal word | Warning |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H341:Germ cell mutagenicity H361:Reproductive toxicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. |
Computed Descriptors for 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
New Products
Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 4-chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) 2,2-Dimethoxy-7-azaspiro[3.5]nonane hydrochloride 1-Boc-4-cyanopiperidine R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDIIMIDAZOLE 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) Methyl 6-methylnicotinate TETRAHYDRO-2H-PYRAN-3-OL tert-Butyl carbazate 2-Methoxyphenothiazine N-methyl -4-piperidone 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 2,4-dihydroxybenzaldehyde 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,6-dichloro-4-nitropyridine 4-Bromo-2-chlorobenzonitrile 1-methylindoline-2,3-dione methyl 4-ethyl-3-ethynylbenzoate Methyl phenyl sulfoneRelated products of tetrahydrofuran
You may like
-
65497-29-2 99%View Details
65497-29-2 -
76272-56-5 Endo-3-Amino-9-methyl-9-Azabicuclononane 99%View Details
76272-56-5 -
18979-61-8 99%View Details
18979-61-8 -
3-acetyl pyridine 99%View Details
350-03-8 -
ketosulfone 221615-75-4 99%View Details
221615-75-4 -
66422-95-5 99%View Details
66422-95-5 -
2-Hydro-4-methoxy-phenyl-phenylmethanone 99%View Details
131-57-7 -
26218-04-2 99%View Details
26218-04-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.