7-Amino-4-methyl-3-coumarinylacetic acid
Synonym(s):2H-1-Benzopyran-3-acetic acid;AMCA-H;Aminomethyl coumarin acetic acid
- CAS NO.：106562-32-7
- Empirical Formula: C12H11NO4
- Molecular Weight: 233.22
- MDL number: MFCD00081051
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:33
What is 7-Amino-4-methyl-3-coumarinylacetic acid?
Description
AMCA is fluorescent protein labeling agent. It contains an N-hydroxysuccinimide ester that reacts with lysine residues to form photostable amide links. Upon activation with UV light, AMCA displays emission maxima of 400-460 nm. It has commonly been used in multiplex immunophenotyping applications.
The Uses of 7-Amino-4-methyl-3-coumarinylacetic acid
7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID is a blue fluorescent dye. Its desirable properties include a relatively large Stoke's shift and resistance to photobleaching. 7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID is used as contrasting probes for double and triple labeling in im
The Uses of 7-Amino-4-methyl-3-coumarinylacetic acid
Non-Activated, Amine-Reactive, fluorescent probe
Properties of 7-Amino-4-methyl-3-coumarinylacetic acid
| Boiling point: | 512.2±50.0 °C(Predicted) |
| Density | 1.391±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMF: soluble |
| form | powder to crystal |
| pka | 3.80±0.10(Predicted) |
| color | Light yellow to Brown |
| λmax | 344nm(Buffer)(lit.) |
| BRN | 7927205 |
Safety information for 7-Amino-4-methyl-3-coumarinylacetic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 7-Amino-4-methyl-3-coumarinylacetic acid
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