6BETA-HYDROXYTESTOSTERONE

Description

CYP3A4 and CYP3A5 are cytochrome P450 enzymes whose expression is induced by glucocorticoids and certain xenobiotics, including many drugs and chemical carcinogens. They mediate the metabolism of xenobiotics as well as certain endobiotics, including steroid hormones. CYP3A4 and CYP3A5 are cytochrome P450 enzymes whose expression is induced by glucocorticoids and certain xenobiotics, including many drugs and chemical carcinogens. They mediate the metabolism of xenobiotics as well as certain endobiotics, including steroid hormones. 6β-hydroxy Testosterone is a major metabolite produced from testosterone by the actions of CYP3A4 and CYP3A5, accounting for 75-80% of all metabolites formed from testosterone. The biological effects of 6β-hydroxy testosterone have been poorly studied.

Chemical properties

White Solid

The Uses of 6BETA-HYDROXYTESTOSTERONE

A metabolite of Testosterone. CONTROLLED SUBSTANC

The Uses of 6BETA-HYDROXYTESTOSTERONE

A metabolite of Testosterone (T155000). CONTROLLED SUBSTANCE

Definition

ChEBI: A 17beta-hydroxy steroid that is testosterone bearing an additional hydroxy substituent at the 6beta-position.

General Description

A Certified Spiking Solution^? suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from clinical and diagnostic testing to endocrinology and sports testing. 6?-Hydroxytestosterone is a major urinary metabolite of testosterone, a hormone from the androgen group of steroids. Testosterone is an important sex hormone and anabolic steroid used as a performance-enhancing drug.