6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid)
- CAS NO.：134-47-4
- Empirical Formula: C21H16N2O9S2
- Molecular Weight: 504.49
- MDL number: MFCD00035715
- EINECS: 205-142-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-31 14:38:37
What is 6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid)?
The Uses of 6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid)
7,7''-(Carbonylbis(azanediyl))bis(4-hydroxynaphthalene-2-sulfonic acid) (cas# 134-47-4) is a pharmacologically active compound capable of selective nonbisphosphonate inhibition of human geranylgeranyl diphosphate synthase, and inhibition of shikimate dehydrogenase and shikimate kinase in shikimate pathway of Helicobacter pylori.
What are the applications of Application
AMI-1, free acid is a chemical shown to inhibit arginine, in vitro, with no inhibitory effect on lysine
Preparation
7,7' -Urylenebis(4-hydroxynaphthalene-2- sulfonic acid) [134-47-4] , J acid urea, carbonyl J acid, is produced by reacting the sodium salt of J acid with phosgene in aqueous solution at 30℃ and maintaining alkalinity with sodium carbonate. After being heated to 80℃, the product is salted out with sodium chloride (yield ca. 100 %). It is used to produce C.I. Direct Orange 26; C.I. Direct Reds 4, 14, 23, and 80; and C.I. Direct Brown 112.
Properties of 6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid)
| Density | 1.798±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO: 83.33 mg/mL (165.18 mM) |
| pka | -0.17±0.40(Predicted) |
| form | Solid |
| color | Light brown to brown |
| CAS DataBase Reference | 134-47-4(CAS DataBase Reference) |
| EPA Substance Registry System | 7,7'-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid] (134-47-4) |
Safety information for 6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid)
| Signal word | Warning |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H334:Sensitisation, respiratory |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P285:In case of inadequate ventilation wear respiratory protection. P304+P341:IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. P342+P311:IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. P403:Store in a well-ventilated place. |
Computed Descriptors for 6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid)
6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid) manufacturer
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![7,7'-(carbonyldiimino)bis[4-hydroxy-3-[(2-methyl-4-sulphophenyl)azo]naphthalene-2-sulphonic] acid](https://img.chemicalbook.in/CAS/GIF/33025-12-6.gif)
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