6-NITROVERATRYL CHLOROFORMATE
Synonym(s):6-Nitroveratryl chloroformate;6-Nitroveratryloxycarbonyl chloride;NVOC chloride;NVOC-Cl
- CAS NO.：42855-00-5
- Empirical Formula: C10H10ClNO6
- Molecular Weight: 275.64
- MDL number: MFCD00143507
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:20:21
What is 6-NITROVERATRYL CHLOROFORMATE?
The Uses of 6-NITROVERATRYL CHLOROFORMATE
4,5-Dimethoxy-2-nitrobenzyl chloroformate is used as a reagent for protection of amines, for use in N-protection of bases in nucleotide synthesis, photochemical protecting groups in organic synthesis. It is used as pharmaceutical intermediate.
The Uses of 6-NITROVERATRYL CHLOROFORMATE
4,5-Dimethoxy-2-nitrobenzyl chloroformate (NVOC-Cl) is a photolabile protecting reagent, commonly used in peptide or nucleotide synthesis to protect amines and hydroxyl groups. General applications are:
- Preparation of inactive, caged protein conjugates which can be activated by irradiating near-ultraviolet light.
- Solid-phase synthesis of base-sensitive S-acylthioethyl (SATE)-prooligonucleotides.
- Modification of surface properties by introducing photocleavable NVOC moiety into chitosan to control cell attachment.
Properties of 6-NITROVERATRYL CHLOROFORMATE
| Melting point: | 125 °C (dec.)(lit.) |
| Boiling point: | 396.4±42.0 °C(Predicted) |
| Density | 1.399±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| color | Pale yellow |
| Water Solubility | Soluble in methanol, acetone. Reacts with water. |
| Sensitive | Moisture & Light Sensitive |
| BRN | 2389168 |
Safety information for 6-NITROVERATRYL CHLOROFORMATE
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 6-NITROVERATRYL CHLOROFORMATE
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 1-AMino-cyclobutaneMethanol HCl TETRABUTYLAMMONIUM CYANIDE 3-Amino-3-(3-fluorophenyl)propanoic acid 3-Amino-3-(4-methylphenyl)propionic acid 3-AMINO-3-(3-CHLORO-PHENYL)-PROPIONIC ACID Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4 - fluoro- 2 - methoxy- 5 - nitroaniline 1-(2-amino-5-hydroxy phenyl)propan-1-one tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-amino-5-nitrobenzonitrile (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanideRelated products of tetrahydrofuran
You may like
-
4,5-Dimethoxy-2-nitrobenzyl chloroformate CAS 42855-00-5View Details
42855-00-5 -
4,5-Dimethoxy-2-nitrobenzyl chloroformate CAS 42855-00-5View Details
42855-00-5 -
10442-39-4 TETRABUTYLAMMONIUM CYANIDE 98+View Details
10442-39-4 -
3-Amino-3-(3-fluorophenyl)propanoic acid 98+View Details
117391-51-2 -
10442-39-4 TETRABUTYLAMMONIUM CYANIDE 98+View Details
10442-39-4 -
68208-21-9 98+View Details
68208-21-9 -
3-Amino-3-(3-fluorophenyl)propanoic acid 98+View Details
117391-51-2 -
3-Amino-3-(4-methylphenyl)propionic acid 68208-18-4 98+View Details
68208-18-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.