6-Methylpyridazin-3(2H)-one

CAS NO.：13327-27-0
Empirical Formula: C5H6N2O
Molecular Weight: 110.11
MDL number: MFCD00039720
EINECS: 236-367-0
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-27 22:41:22

What is 6-Methylpyridazin-3(2H)-one?

The Uses of 6-Methylpyridazin-3(2H)-one

6-?Methyl-?3-?pyridazinone is a lignin-based dye used on wool. 6-?Methyl-?3-?pyridazinone is also used as a reactant for the synthesis of C-?(1-?aryl-?cyclohexyl)?-?methylamine derivatives as selective, orally available inhibitors of dipeptidyl peptidase IV, imidazopyridazinone derivatives as PDE7 inhibitors and pyridazinone derivatives with an arylpiperazinylalkyl chain as a potentent, orally active, antinociceptive agent.

Definition

ChEBI: 6-Methylpyridazin-3(2H)-one is a member of pyridazines.

Synthesis Reference(s)

Synthesis, p. 1158, 1994 DOI: 10.1055/s-1994-25663

Properties of 6-Methylpyridazin-3(2H)-one

Melting point:	143-145°C
Density	1.22±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
form	powder to crystal
pka	11.51±0.40(Predicted)
color	Light yellow to Amber to Dark green
BRN	109928
CAS DataBase Reference	13327-27-0(CAS DataBase Reference)

Safety information for 6-Methylpyridazin-3(2H)-one

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.