6-Methoxyquinoline
Synonym(s):6-Methoxyquinoline
- CAS NO.：5263-87-6
- Empirical Formula: C10H9NO
- Molecular Weight: 159.18
- MDL number: MFCD00006800
- EINECS: 226-077-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:16:00
What is 6-Methoxyquinoline?
Chemical properties
colorless to light yellow liquid
The Uses of 6-Methoxyquinoline
6-Methoxyquinoline is a useful sythetic intermediate
The Uses of 6-Methoxyquinoline
6-Methoxyquinoline is used as a precursor in the synthesis of:
- Fluorescent zinc and chlorine sensors.
- 5-Amino-2-aroylquinolines as potent tubulin polymerization inhibitors.
- 3-Fluoro-6-methoxyquinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase.
- Cobalt-based ternary metal-organic complex as single?ion magnets.
What are the applications of Application
6-Methoxyquinoline is A useful sythetic intermediate
Definition
ChEBI: An aromatic ether that is quinoline substituted at position 6 by a methoxy group.
Synthesis Reference(s)
Journal of the American Chemical Society, 68, p. 1584, 1946 DOI: 10.1021/ja01212a062
Properties of 6-Methoxyquinoline
| Melting point: | 18-20 °C (lit.) |
| Boiling point: | 140-146 °C/15 mmHg (lit.) |
| Density | 1.15 g/mL at 20 °C (lit.) |
| refractive index | n |
| FEMA | 4640 | 6-METHOXYQUINOLINE |
| Flash point: | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | soluble in Alcohol |
| pka | 5.03(at 20℃) |
| form | Granular Powder |
| color | White to cream |
| Odor | heavy sweet |
| Water Solubility | insoluble |
| Sensitive | Light Sensitive |
| JECFA Number | 2157 |
| BRN | 115244 |
| CAS DataBase Reference | 5263-87-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Quinoline, 6-methoxy-(5263-87-6) |
| EPA Substance Registry System | Quinoline, 6-methoxy- (5263-87-6) |
Safety information for 6-Methoxyquinoline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 6-Methoxyquinoline
6-Methoxyquinoline manufacturer
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