6-Hydroxy-2-naphthoic acid
- CAS NO.：16712-64-4
- Empirical Formula: C11H8O3
- Molecular Weight: 188.18
- MDL number: MFCD00060070
- EINECS: 240-759-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:11
What is 6-Hydroxy-2-naphthoic acid?
Chemical properties
pale brown powder
The Uses of 6-Hydroxy-2-naphthoic acid
6-hydroxy-2-naphthoic acid is used for preparation engineering plastics, organic pigments, liquid crystal materials, medicine, particularly as a monomer of heat-resistant material.
The Uses of 6-Hydroxy-2-naphthoic acid
6-Hydroxy-2-naphthoic acid may be used in the synthesis of 5-bromo-6-hydroxy-2-naphthoic acid and liquid-crystalline epoxy resins.
Definition
ChEBI: 6-Hydroxy-2-naphthoic acid is a naphthoic acid.
General Description
6-Hydroxy-2-naphthoic acid is a hydroxynaphthoic acid derivative. Whole cells of the recombinant Escherichia coli strain expressing CYP199A2 were reported to catalyze the regioselective oxidation of 6-hydroxy-2-naphthoic acid to afford 6,7-dihydroxynaphthoic acid. It can form co-crystals with caffeine.
Flammability and Explosibility
Non flammable
Synthesis
6-Hydroxy-2-naphthoic acid [16712-64-4], mp 245 – 248℃, is synthesized by carboxylation of the potassium salt of 2-naphthol at 170 – 230℃. It couples with diazo compounds in the 5-position and undergoes sulfonation in the 4- and 7-positions.
Properties of 6-Hydroxy-2-naphthoic acid
| Melting point: | 240-250 °C (lit.) |
| Boiling point: | 283.17°C (rough estimate) |
| Density | 1.2100 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.6400 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Insoluble in water |
| pka | 4.34±0.30(Predicted) |
| form | Powder |
| color | Pale brown |
| Water Solubility | 99mg/L at 20℃ |
| BRN | 2692084 |
| CAS DataBase Reference | 16712-64-4(CAS DataBase Reference) |
| EPA Substance Registry System | 6-Hydroxy-2-naphthoic acid (16712-64-4) |
Safety information for 6-Hydroxy-2-naphthoic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H303:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 6-Hydroxy-2-naphthoic acid
6-Hydroxy-2-naphthoic acid manufacturer
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product: 6-Hydroxy-2-Napthoic Acid 16712-64-4 99.00%
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