6-Cyano-2-naphthol
Synonym(s):6-Hydroxy-2-naphthonitrile;2-Cyano-6-hydroxynaphthalene;2-Cyano-6-naphthol;2-Hydroxy-6-naphthonitrile;6-Cyano-2-hydroxynaphthalene
- CAS NO.：52927-22-7
- Empirical Formula: C11H7NO
- Molecular Weight: 169.18
- MDL number: MFCD01863480
- EINECS: 628-663-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-08-05 19:35:02
What is 6-Cyano-2-naphthol?
Chemical properties
Brown Crystalline Solid. 6-Cyano-b-naphthol [52927-22-7], 6-cyano2-hydroxynaphthalene, 6-hydroxy-2-naphthoic acid nitrile, Mr 169.17, mp 166 – 167℃ This nitrile is used as an intermediate for the production of liquid crystals and monoamino-oxidase-inhibiting naphthalene-2-oxyalkylamines, which are used as antidepressive agents.
The Uses of 6-Cyano-2-naphthol
Intermediate of Nafamostat mesilate (N210000).
The Uses of 6-Cyano-2-naphthol
Reactant for:
- Palladium-catalyzed reduction
- Nickel-catalyzed cross-coupling reactions
- Palladium-catalyzed Heck reactions
What are the applications of Application
6-Cyano-2-naphthol is An intermediate of Nafamostat mesilate
General Description
6-Cyano-2-naphthol (6CN2) is an aromatic alcohol that can be synthesized from 6-bromo-2-naphthol. It is a superphotoacid with the ground state pKa* value of 8.4 and excited state pKavalue of 0.2, respectively. 6CN2 protonates PANI-ES (polyaniline emeraldine salt) to form PANI-EB (emeraldine base), which shows enhanced conductivity. The proton-transfer kinetics and photophysical behavior of 6CN2 have been investigated.
Properties of 6-Cyano-2-naphthol
| Melting point: | 165.5-170.5 °C (lit.) |
| Boiling point: | 383.1±15.0 °C(Predicted) |
| Density | 1.28±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Ethanol, Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 8.57±0.40(Predicted) |
| color | Pale Brown to Brown |
| CAS DataBase Reference | 52927-22-7(CAS DataBase Reference) |
Safety information for 6-Cyano-2-naphthol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 6-Cyano-2-naphthol
New Products
Cyclobutanone (R)-(-)-2-Amino-1-propanol Fmoc-OSu 5-bromo-4-fluoro-2-nitrobenzaldehyde 2-Amino-2-(4-methylphenyl)acetic acid 1-(2-Chloroethyl)pyrrolidine Hydrochloride 2,4-Dihydroxybenzaldehyde Obidoxime hydrochloride API Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Dipropyl disulfide N-Vinylformamide 4 pentyn 1 ol Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
You may like
-
52927-22-7 6-CYANO-2-NAPHTHOL 99%View Details
52927-22-7 -
52927-22-7 95-99%View Details
52927-22-7 -
6-Hydroxy-2-naphthonitrile CAS 52927-22-7View Details
52927-22-7 -
6-Cyano-2-naphthol CAS 52927-22-7View Details
52927-22-7 -
545445-44-1 3-Morpholino-1-(4-(2-oxopiperidin-1-yl) phenyl)-5,6-dihyropyridin-2-(1H)-one 98%View Details
545445-44-1 -
6629-04-5 98%View Details
6629-04-5 -
4-(4-Αminophenyl)-3-Morpholinone 98%View Details
438056-69-0 -
1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one 1267610-26-3 98%View Details
1267610-26-3
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.