6-Chloropurine ribonucleoside
- CAS NO.：2004-06-0
- Empirical Formula: C10H11ClN4O4
- Molecular Weight: 286.67
- MDL number: MFCD00005738
- EINECS: 217-904-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-16 09:56:25
What is 6-Chloropurine ribonucleoside?
Chemical properties
white to light yellow crystal powde
The Uses of 6-Chloropurine ribonucleoside
6-CHLOROPURINE RIBOSIDE acts as a reactant in the synthesis of isozyme-specific enzyme inhibitors as well as in the preparation of dog coronary artery receptor agonists.
Purification Methods
Purify the riboside by suspending the dry solid (~12 g) in hot MeOH (130 mL) and then adding enough hot H2O (~560mL) to cause solution, filter and set aside at 5o overnight. The colourless crystals of the riboside are filtered off, washed with Me2CO, Et2O and dried at 60o/0.1mm. More material can be obtained by evaporating the filtrate to dryness and recrystallisation of the residue from MeOH/H2O (2:1) (15mL/g). It has max 264nm ( 9140) in H2O. [Robins Biochemical Preparations 10 145 1963, Baker et al. J Org Chem 22 954 1957.]
Properties of 6-Chloropurine ribonucleoside
| Melting point: | 158-162 °C (dec.)(lit.) |
| Boiling point: | 614.8±65.0 °C(Predicted) |
| Density | 1.7303 (rough estimate) |
| refractive index | -45 ° (C=0.8, H2O) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| form | Powder |
| pka | 13.06±0.70(Predicted) |
| color | Yellow to Green |
| CAS DataBase Reference | 2004-06-0(CAS DataBase Reference) |
Safety information for 6-Chloropurine ribonucleoside
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 6-Chloropurine ribonucleoside
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