2-Chloro-6-methylpyridine
Synonym(s):6-Chloro-2-picoline
- CAS NO.：18368-63-3
- Empirical Formula: C6H6ClN
- Molecular Weight: 127.57
- MDL number: MFCD00006245
- EINECS: 242-241-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:24
What is 2-Chloro-6-methylpyridine?
Description
2-Chloro-6-methylpyridine (2C6MP) is a strong inhibitor of methane monooxygenase, a key enzyme in the aerobic oxidation of methane (CH4). It belongs to the pesticide nitropyridine group of compounds. Studies have shown that 2C6MP has the least effect on CH4 oxidation at concentrations of 0.1 mM and 1 mM, but at a concentration of 10 mM, 2C6MP inhibits CH4 oxidation for >20 months. Low concentrations of 2C6MP did not inhibit Methylophilaceae, while high concentrations of 2C6MP inhibited Methylophilaceae by only 7.8 ± 1.1%[1].
Chemical properties
Light yellow liquid
The Uses of 2-Chloro-6-methylpyridine
2-Chloro-6-methylpyridine has been used for experimental FTIR and FT-Raman spectroscopic analyses, as well as for conformational studies.
References
[1] E. O’LOUGHLIN. Inhibition of Microbial Methane Oxidation by 2-Chloro-6-Methylpyridine[J]. bioRxiv?: the preprint server for biology, 2022. DOI:10.1101/2022.10.13.512149.
Properties of 2-Chloro-6-methylpyridine
| Boiling point: | 64-68 °C10 mm Hg(lit.) |
| Density | 1.167 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 165 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Liquid |
| pka | 1.10±0.10(Predicted) |
| Specific Gravity | 1.167 |
| color | Clear colorless to light yellow |
| BRN | 107187 |
| InChI | InChI=1S/C6H6ClN/c1-5-3-2-4-6(7)8-5/h2-4H,1H3 |
| CAS DataBase Reference | 18368-63-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Cl-6-(CH3)-pyridine(18368-63-3) |
| EPA Substance Registry System | Pyridine, 2-chloro-6-methyl- (18368-63-3) |
Safety information for 2-Chloro-6-methylpyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Chloro-6-methylpyridine
| InChIKey | GXZDYRYYNXYPMQ-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC(C)=CC=C1 |
2-Chloro-6-methylpyridine manufacturer
JSK Chemicals
3Y
Phone:+91-9879767984
Whatsapp: +91-9879767970
product: 2-Chloro-6-methylpyridine, 98% 18368-63-3 99%
ALS India Life Sciences Pvt. Ltd
2Y
Phone:+91-8977036378
Whatsapp: +91 8008166674
product: 6-Chloro-2-picoline 18368-63-3 99.60%
SAKEM LLP
1Y
Phone:+91-9676889998
Whatsapp: +91-9676889998
product: 2-Chloro-6-Methyl Pyridine. 18368-63-3 98%
ASM Organics
Andhra Pradesh
Phone:91-9866122393
Whatsapp: 91-9866122393
product: 6-Chloro-ALPHA-picoline
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