6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE

CAS NO.：820231-95-6
Empirical Formula: C15H20N2O2
Molecular Weight: 260.33
MDL number: MFCD09971128
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE?

What are the applications of Application

Sazetidine A dihydrochloride is an agonist of nicotinic acetylcholine receptors

Biological Activity

Subtype-selective α 4 β 2 nicotinic acetylcholine receptor ligand (K i values are 0.26 and 54 nM at α 4 β 2 and α 3 β 4 receptors respectively). May act as a silent desensitizer or as an agonist (EC 50 = 1.1 nM for nAChR-stimulated dopamine release). Exhibits analgesic activity in vivo .

Properties of 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE

storage temp.	Desiccate at +4°C
form	White to off-white solid.

Safety information for 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE

Computed Descriptors for 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE

New Products

2-Bromo-4-hydroxypyridine Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Cis-Tosylate 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 1-aminocyclobutanecarbonitrile hydrochloride AMINO-O-TOLYL-ACETIC ACID 1-Aminocyclobutanecarboxylic Acid Hydrochloride AMINO(2-BROMOPHENYL)ACETIC ACID 6-BROMOTETRAZOLO[1,5-A]PYRIDINE 3-Oxocyclobutanecarboxylic acid METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 2-(2-Bromophenyl)ethanol Boc-D-Glu(OMe)-OMe 2,5 Dibromopyridine Ethyl 4-hydroxy-3-oxobutanoate Dimethyl (2S)-2-((tert-butoxycarbonyl)amino)-4-(cyanomethyl)pentanedioate 1-(3-Chlorophenyl)piperazine hydrochloride

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