6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE

CAS NO.：820231-95-6
Empirical Formula: C15H20N2O2
Molecular Weight: 260.33
MDL number: MFCD09971128
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE?

What are the applications of Application

Sazetidine A dihydrochloride is an agonist of nicotinic acetylcholine receptors

Biological Activity

Subtype-selective α 4 β 2 nicotinic acetylcholine receptor ligand (K i values are 0.26 and 54 nM at α 4 β 2 and α 3 β 4 receptors respectively). May act as a silent desensitizer or as an agonist (EC 50 = 1.1 nM for nAChR-stimulated dopamine release). Exhibits analgesic activity in vivo .

Properties of 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE

storage temp.	Desiccate at +4°C
form	White to off-white solid.

Safety information for 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE

Computed Descriptors for 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE

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