5,6-Dimethoxyindole
- CAS NO.:14430-23-0
- Empirical Formula: C10H11NO2
- Molecular Weight: 177.2
- MDL number: MFCD00005675
- EINECS: 238-402-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-24 18:13:45
What is 5,6-Dimethoxyindole?
Chemical properties
Beige powder
The Uses of 5,6-Dimethoxyindole
5,6-Dimethoxyindole is an indole derivative as analgesic antiinflammatory. It was used in the synthesis of N-benzyl-N-cyclopropyl-5,6-dimethoxyindole-3-glyoxalamide.
What are the applications of Application
5,6-Dimethoxyindole was used in the synthesis of N-benzyl-N-cyclopropyl-5,6-dimethoxyindole-3-glyoxalamide.
Reactant in synthesis of indolylhydroxyoxindoles via enantioselective Friedel-Crafts reaction
Reactant in synthesis of benzyl trimethoxyindoles
Reactant for synthesis of benzoylpiperazinyl-indolyl ethane dione derivatives as HIV-1 inhibitors
Reactant for synthesis of 1-aroylindole 3-aroylindoles combretastatin A-4 analogs as antitumor agents and tubulin polymerization inhibitors
Reactant for preparation of tryptophanol derivatives via the Grignard reaction
Synthesis Reference(s)
Journal of the American Chemical Society, 75, p. 5887, 1953 DOI: 10.1021/ja01119a030
Synthesis of 5,6-Dimethoxyindoles and 5,6-Dimethoxyoxindoles. A New Synthesis of Indoles DOI: 10.1021/ja01619a049
Properties of 5,6-Dimethoxyindole
| Melting point: | 154-157 °C (lit.) |
| Boiling point: | 198°C 8mm |
| Density | 1.182±0.06 g/cm3(Predicted) |
| Flash point: | 198°C/8mm |
| storage temp. | Sealed in dry,Room Temperature |
| form | Powder |
| pka | 16.93±0.30(Predicted) |
| color | Beige |
| Water Solubility | Insoluble in water. |
| λmax | 306nm(EtOH)(lit.) |
| BRN | 5683 |
| CAS DataBase Reference | 14430-23-0(CAS DataBase Reference) |
Safety information for 5,6-Dimethoxyindole
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 5,6-Dimethoxyindole
| InChIKey | QODBZRNBPUPLEZ-UHFFFAOYSA-N |
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