5-(Trifluoromethyl)pyridine-2-carboxylic acid
Synonym(s):5-(Trifluoromethyl)picolinic acid
- CAS NO.：80194-69-0
- Empirical Formula: C7H4F3NO2
- Molecular Weight: 191.11
- MDL number: MFCD04113632
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:46:02
What is 5-(Trifluoromethyl)pyridine-2-carboxylic acid?
The Uses of 5-(Trifluoromethyl)pyridine-2-carboxylic acid
5-(Trifluoromethyl)pyridine-2-carboxylic acid is an intermediate used in the synthesis of β-secretase (BACE) inhibitors.
The Uses of 5-(Trifluoromethyl)pyridine-2-carboxylic acid
5-(Trifluoromethyl)pyridine-2-carboxylic acid is an intermediate used in the synthesis of β-secretase (BACE) inhibitors.
Properties of 5-(Trifluoromethyl)pyridine-2-carboxylic acid
| Melting point: | 135-137°C |
| Boiling point: | 273.7±40.0 °C(Predicted) |
| Density | 1.484±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Powder |
| pka | 3.13±0.10(Predicted) |
| color | Pale brown |
| Water Solubility | Slightly soluble in water. |
| CAS DataBase Reference | 80194-69-0(CAS DataBase Reference) |
Safety information for 5-(Trifluoromethyl)pyridine-2-carboxylic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-(Trifluoromethyl)pyridine-2-carboxylic acid
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