5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE
Synonym(s):3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride;DMA
- CAS NO.：1214-79-5
- Empirical Formula: C8H12ClN7O
- Molecular Weight: 257.68
- MDL number: MFCD00069207
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-13 16:10:10
What is 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE?
The Uses of 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE
5-(N,N-Dimethyl)amiloride hydrochloride is a selective blocker of Na2/H+ antiport. 5-(N,N-Dimethyl)amiloride hydrochloride has been investigated for its ability to reduce inflammatory pain.
Biochem/physiol Actions
Selective blocker of Na+/H+ antiport; IC50 = 6.9 μM.
Properties of 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE
| Melting point: | 216-217 °C |
| Density | 1.68±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | Yellow solid. |
| pka | 8.66±0.46(Predicted) |
Safety information for 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE
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