5-Methyltetrahydrofolic acid
- CAS NO.：134-35-0
- Empirical Formula: C20H25N7O6
- Molecular Weight: 459.46
- MDL number: MFCD00900533
- EINECS: 603-809-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-30 16:22:46
What is 5-Methyltetrahydrofolic acid?
Chemical properties
Off-White Solid
The Uses of 5-Methyltetrahydrofolic acid
5-Methyltetrahydrofolic acid is a metabolite of Folic acid; inhibits photosensitization reactions and strand breaks in DNA. 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) can be used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by LC-MS.
The Uses of 5-Methyltetrahydrofolic acid
5-Methyltetrahydrofolic acid-(glutamic acid-13C5) can be used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by LC-MS.
General Description
5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite. It plays an important role in the synthesis of methionine from homocysteine by donating methyl group.
5-Methyltetrahydrofolic acid-(glutamic acid-13C5) is an isotope of vitamin B9 wherein all the five glutamate carbons are replaced by 13C6 carbon.
Properties of 5-Methyltetrahydrofolic acid
| Melting point: | >300°C (dec.) |
| Density | 1.62±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Aqueous Base (Slightly, Sonicated) |
| form | Solid |
| pka | 3.51±0.10(Predicted) |
| color | Pale Beige |
| Stability: | Hygroscopic |
Safety information for 5-Methyltetrahydrofolic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-Methyltetrahydrofolic acid
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