Imidazolidine

The Uses of Imidazolidine

The imidazolines, was discovered at American Cyanamid in the early 1980s. Extensive research has led to the development of four commercial compounds: imazapyr, imazamethabenzmethyl, imazethapyr, and imazaquin. Like the sulfonylureas, the imidazolines are extremely active at low rates.

Definition

ChEBI: Imidazolidine is a saturated organic heteromonocyclic parent, a member of imidazolidines and an azacycloalkane.

Structure and conformation

Dihydroimidazole is a five-membered, nonplanar, and nonaromatic heterocycle, derived by the partial reduction of one of the two double bonds of the imidazole ring. The dihydroimidazoles are also referred to as imidazolines and there are three possible regioisomeric forms: 4,5-dihydroimidazole (2-imidazoline), 2,5-dihydroimidazole (3-imidazoline), and 2,3- dihydroimidazole (4-imidazoline). The 2- and 3-imidazolines contain an imine center, while 4-imidazoline contains an alkene substructure. Among these three isomeric forms, the chemistry of 2-imidazoline is more developed than 3- and 4-imidazolines.