5-METHOXYGRAMINE
Synonym(s):3-(Dimethylaminomethyl)-5-methoxyindole;NSC 88885
- CAS NO.：16620-52-3
- Empirical Formula: C12H16N2O
- Molecular Weight: 204.27
- MDL number: MFCD00005630
- EINECS: 240-669-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:21:58
What is 5-METHOXYGRAMINE?
Chemical properties
white to almost white crystalline powder
The Uses of 5-METHOXYGRAMINE
• ;Reactant for preparation of dopamine D2 receptor antagonists1• ;Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction2• ;Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands3• ;Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents4• ;Reactant for preparation of in
The Uses of 5-METHOXYGRAMINE
- Reactant for preparation of dopamine D2 receptor antagonists
- Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction
- Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands
- Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents
- Reactant for preparation of indolylmethanesulfonamide and its methoxy derivatives
Properties of 5-METHOXYGRAMINE
| Melting point: | 123-126 °C (lit.) |
| Boiling point: | 342.77°C (rough estimate) |
| Density | 1.0565 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Refrigerator (+4°C) |
| pka | 16.70±0.30(Predicted) |
| BRN | 170533 |
| CAS DataBase Reference | 16620-52-3(CAS DataBase Reference) |
Safety information for 5-METHOXYGRAMINE
Computed Descriptors for 5-METHOXYGRAMINE
New Products
Dexamethasone Sodium Phosphate p-Anisaldehyde m-Tolualdehyde 2-Bromobenzaldehyde 4-Fluorobenzaldehyde 1-Propyl-4-piperidone 3-Amino-3-(3-fluorophenyl)propanoic acid Raloxifene EP Impurity D N-Nitroso Nortriptyline Nitroso Irbesartan 2-(p-Tolyl)acetaldehyde Sulfonic acid Impurity 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one 5-Chloro-2-Methoxy-4-Picoline 2-Amino-6-nitrobenzoic Acid (6-Nitroanthranilic acid) Cis-3,5 Diacetoxy-1-cyclopentene 3-Bromo-2-Methoxy-4-Methylpyridine 2-Amino-5-Chloro-3-Nitro-6-picoline 3-Methoxy-5-methylpyrazin-2-amine Pentachlorobenzonitrile Budesonide Nicotinic acid RAPAMYCIN Alpha CyclodextrinRelated products of tetrahydrofuran
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