5-METHOXYGRAMINE

Synonym(s):3-(Dimethylaminomethyl)-5-methoxyindole;NSC 88885

CAS NO.：16620-52-3
Empirical Formula: C12H16N2O
Molecular Weight: 204.27
MDL number: MFCD00005630
EINECS: 240-669-8
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 01:24:03

What is 5-METHOXYGRAMINE?

Chemical properties

white to almost white crystalline powder

The Uses of 5-METHOXYGRAMINE

• ;Reactant for preparation of dopamine D2 receptor antagonists1• ;Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction2• ;Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands3• ;Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents4• ;Reactant for preparation of in

The Uses of 5-METHOXYGRAMINE

Reactant for preparation of dopamine D2 receptor antagonists
Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction
Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands
Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents
Reactant for preparation of indolylmethanesulfonamide and its methoxy derivatives

Properties of 5-METHOXYGRAMINE

Melting point:	123-126 °C (lit.)
Boiling point:	342.77°C (rough estimate)
Density	1.0565 (rough estimate)
refractive index	1.6000 (estimate)
storage temp.	Refrigerator (+4°C)
pka	16.70±0.30(Predicted)
BRN	170533
CAS DataBase Reference	16620-52-3(CAS DataBase Reference)