5-Chloroquinolin-8-amine
- CAS NO.：5432-09-7
- Empirical Formula: C9H7ClN2
- Molecular Weight: 178.62
- MDL number: MFCD00461243
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:50:37
What is 5-Chloroquinolin-8-amine?
Chemical properties
Light yellow needle-like crystals. Melting point 87℃, insoluble in water, easily soluble in ethanol and ether.
The Uses of 5-Chloroquinolin-8-amine
5-Chloroquinolin-8-amine can be used as a dye intermediate.
Synthesis
Mix 5-chloro-8-nitroquinoline and 50% acetic acid, add iron powder, then neutralize with concentrated ammonia water to pH 8, and then obtain 5-Chloroquinolin-8-amine by steam distillation.
Properties of 5-Chloroquinolin-8-amine
| Melting point: | 70-72 °C |
| Boiling point: | 354.4±27.0 °C(Predicted) |
| Density | 1.363±0.06 g/cm3(Predicted) |
| pka | 3.02±0.12(Predicted) |
| color | Yellow |
Safety information for 5-Chloroquinolin-8-amine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for 5-Chloroquinolin-8-amine
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