5-Chloroisatin

Synonym(s):5-Chloro-1H-indole-2,3-dione

CAS NO.：17630-76-1
Empirical Formula: C8H4ClNO2
Molecular Weight: 181.58
MDL number: MFCD00014567
EINECS: 241-614-0
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-02 17:37:48

What is 5-Chloroisatin?

Chemical properties

pale yellow to reddish or yellow-brownish powder

The Uses of 5-Chloroisatin

5-Chloroisatin is a reagent used in the synthesis of Schiff bases through the reaction with 2-methyl-4-nitroaniline or 4-amino-4,5-dihydro-1H-1,2,3-triazole-5-one.

What are the applications of Application

5-Chloroisatin is 5-Chloroisatin is a reagent used in the synthesis of Schiff bases through the reaction with 2-methyl-4-nitroaniline or 4-amino-4,5-dihydro-1H-1,2,3-triazole-5-one.

Definition

ChEBI: 5-Chloro-1H-indole-2,3-dione is a member of indoles. It has a role as an anticoronaviral agent.

General Description

5-Chloroisatin reacts with substituted 4-amino-4,5-dihydro-1H-1,2,4-triazole-5-ones to yield Schiff bases.

Properties of 5-Chloroisatin

Melting point:	254-258 °C (lit.)
Density	1.3743 (rough estimate)
refractive index	1.5560 (estimate)
storage temp.	Sealed in dry,Room Temperature
pka	8.65±0.20(Predicted)
form	Powder
Water Solubility	insoluble
BRN	383759
CAS DataBase Reference	17630-76-1(CAS DataBase Reference)

Safety information for 5-Chloroisatin

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.