5-Bromo-2-methoxyphenol
- CAS NO.：37942-01-1
- Empirical Formula: C7H7BrO2
- Molecular Weight: 203.03
- MDL number: MFCD00673137
- EINECS: 609-492-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-04 16:04:00
What is 5-Bromo-2-methoxyphenol?
Chemical properties
White to off-white crystal
The Uses of 5-Bromo-2-methoxyphenol
The 5-Bromo-2-methoxyphenol is the important intermediate of producing depressor aliskiren.
Synthesis
The 5-bromo-2-methoxyphenol is synthesized by virtue of three steps of reactions as follows: by taking o-methoxyphenol as the raw materials, performing acetylation protection on the phenolic hydroxyl by use of acetic anhydride, and then performing bromination by use of bromine under the catalysis of iron powder, and finally performing deacetylation.
Properties of 5-Bromo-2-methoxyphenol
| Melting point: | 64-70 |
| Boiling point: | 150 °C / 20mmHg |
| Density | 1.585±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | 9.01±0.10(Predicted) |
| color | White to Almost white |
| CAS DataBase Reference | 37942-01-1(CAS DataBase Reference) |
Safety information for 5-Bromo-2-methoxyphenol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 5-Bromo-2-methoxyphenol
| InChIKey | OLSJHVZRUFFIPL-UHFFFAOYSA-N |
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