5-Amino-2-chloropyridine
- CAS NO.：5350-93-6
- Empirical Formula: C5H5ClN2
- Molecular Weight: 128.56
- MDL number: MFCD00006243
- EINECS: 226-322-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 22:51:29
What is 5-Amino-2-chloropyridine?
Chemical properties
Light yellow to brown crystalline powder
The Uses of 5-Amino-2-chloropyridine
5-Amino-2-chloropyridine was used in the synthesis of [2H5]2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine. It was used in identification and evaluation of molecularly imprinted polymers for the selective removal of potentially genotoxic aminopyridine impurities from pharmaceuticals.
Definition
ChEBI: 3-Amino-6-chloropyridine is an aminopyridine.
General Description
5-Amino-2-chloropyridine undergoes Suzuki-Miyaura coupling with sterically hindered 2,6-dimethylphenylboronic acid. It undergoes facile temperature dependent displacement of chloride by bromide via Sandmeyer reaction to yield 2,5-dibromopyridine.
Properties of 5-Amino-2-chloropyridine
| Melting point: | 81-83 °C(lit.) |
| Boiling point: | 205.39°C (rough estimate) |
| Density | 1.2417 (rough estimate) |
| refractive index | 1.5110 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | powder to crystal |
| pka | 1.94±0.10(Predicted) |
| color | White to Brown |
| BRN | 108891 |
| CAS DataBase Reference | 5350-93-6(CAS DataBase Reference) |
Safety information for 5-Amino-2-chloropyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-Amino-2-chloropyridine
| InChIKey | QAJYCQZQLVENRZ-UHFFFAOYSA-N |
5-Amino-2-chloropyridine manufacturer
Ina pharmaceuticals Pvt Ltd
3Y
Phone:+91-7815933367
Whatsapp: +91-78159 33367
product: 5350-93-6 5-Amino-2-Chloropyridine 99%
Lorven Biologics Pvt Ltd
1Y
Phone:+91-8884110005
Whatsapp: +91-8884110005
product: 5350-93-6 2-chloro 5-amino pyridine 98%
ASM Organics
Andhra Pradesh
Phone:91-9866122393
Whatsapp: 91-9866122393
product: 5-Amino-2-chloropyridine
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